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| Name: | Cecilia Gelfi |
| E-mail address: | cecilia.gelfi@unimi.it |
| IBFM position: | Associate Researcher |
| More affiliations: | Department of Biomedical Sciences and Technologies, University of Milano |
Postal address: |
LITA Building - Via Fratelli Cervi, 93 - 20090 Segrate (MI), Italy Tel: +39 02 21717. 503 - Fax +39 02 21717. 558 |
| Research interests: | I
have mostly developed electrophoretic techniques, particularly isoelectric
focusing. I contributed to the development of the technique of isoelectric
focusing in immobilized pH gradients (IPG), which today represents
the most advanced analytical tool in biochemistry and molecular
biology, and represent the core of modern 2D map. Two years ago
I started with proteomic studies on skeletal muscle taking advantage
to the knowledge on separation science of macromolecules. In a first
attempt I focalized my interest into the systematic characterization
of all the protein expressed in the muscle compartment. As tool
we applied first the 2DE for the separation of protein in the 14-100KDa,
but we are now applying new methodologies for structural muscle
proteins characterized by high molecular mass. Our interests are
related to a number of muscles physiological and fisiopathological
problems (i.e. hypoxia adaptation, muscle impairments linked to
genetic disease, effect of micro gravity etc.) , applying the differential
display proteomics. |
| Representative publications: |
Gelfi C, De Palma S,
Ripamonti M, Wait R, Eberini I, Bajracharya A, Marconi C, Schneider
A, Hoppeler H and Cerretelli P. New aspects of altitude adaptation
in Tibetans. A proteomic approach. FASEB J, 2004;
18 (3): 612-614. |
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