Manna Ida

Bio sketch

Natural Sciences graduate

ORCID ID: 0000-0002-4777-7138

Scopus Author ID: 7004414945

Research Topics

• • Genetic-molecular study of neurological diseases with a special interest in biomarker identification for the characterization of the genetic basis of specific inherited diseases (such as Alzheimer disease, Frontotemporal dementia, Multiple Sclerosis and Focal epilepsy.
  • Genetic association studies with candidate gene finalized looking for genetic risk factors.
  • Studies of epigenetics, concerning the non-coding RNA.

Most relevant recent bibliography

• • Quattrone A, Morelli M, Nisticò R, Manna I, Quattrone A. Dropped head syndrome in a patient with FTD-ALS caused by abnormal expansion of C9orf72 gene.. Neurol Sci. 2019 Oct 21
  • Epi25 Collaborative. Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals. Am J Hum Genet. 2019 Aug 1;105(2):267-282
  • Cava C*, Manna I*, Gambardella A, Bertoli G, Castiglioni I. Potential Role of miRNAs as Theranostic Biomarkers of Epilepsy. Mol Ther Nucleic Acids. 2018 Dec 7;13:275-290
  • Manna I, Iaccino E, Dattilo V, Barone S, Vecchio E, Mimmi S, Filippelli E, Demonte G, Polidoro S, Granata A, Scannapieco S, Quinto I, Valentino P, Quattrone A. Exosome-associated miRNA profile as a prognostic tool for therapy response monitoring in multiple sclerosis patients. FASEB J. 2018 Aug;32(8):4241-4246
  • Manna I, Labate A, Borzì G, Mumoli L, Cavalli SM, Sturniolo M, Quattrone A, Gambardella A. An SNP site in pri-miR-124, a brain expressed miRNA gene, no contribution to mesial temporal lobe epilepsy in an Italian sample. Neurol Sci. 2016 Aug;37(8):1335-9
  • Striano P, Serioli E, Santulli L, Manna I, Labate A, Dazzo E, Pasini E, Gambardella A, Michelucci R, Striano S, Nobile C. DEPDC5 mutations are not a frequent cause of familial temporal lobe epilepsy. Epilepsia. 2015 Oct;56(10):e168-71
  • Manna I, Gambardella A, Labate A, Mumoli L, Ferlazzo E, Pucci F., Aguglia U, Quattrone A,. Polymorphism of the multidrug resistance 1 gene MDR1/ABCB1 C3435T and response to antiepileptic drug treatment in temporal lobe epilepsy. Seizure. 2015 Jan 24
  • Manna I, Mumoli L, Labate A, Citrigno L, Ferlazzo E, Aguglia U, Quattrone A, Gambardella A. Autosomal dominant lateral temporal epilepsy (ADLTE): Absence of chromosomal rearrangements in LGI1 gene. Epilepsy Res. 2013 Nov 18
  • Manna I, Labate A, Mumoli L, Ferlazzo E, Aguglia U, Quattrone A, Gambardella A. No evidence for a role of the coding variant of the Toll-like receptor 4 gene in temporal lobe epilepsy. Seizure. 2013 Jun 26
  • Manna I, Labate A, Mumoli L, Ferlazzo E, Aguglia U, Quattrone A, Gambardella A. Failure to confirm association of a polymorphism in KCNMB4 gene with mesial temporal lobe epilepsy. Epilepsy Res. 2013 Apr 25