Research Topics

• • Advanced MRI in neuropsychiatric and neurodegenerative disorders
  • Quantification and molecular characterisation of neurofibrillary tangles by means of PET tracers
  • Advanced MRI for personality neuroscience (studying the neurobiological roots of personality differences)

CV

National Collaborations

• • Prof. Nicola Toschi, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy
  • Prof. Iole Indovina, Department of Medicine and Surgery, Saint Camillus International University of Health and Medical Sciences, Rome, Italy
  • Prof. Francesco Lacquaniti, Laboratory of Neuromotor Physiology, IRCCS Santa Lucia Foundation, Rome, Italy

International Collaborations

• • Prof. James B. Rowe, Dept. of Clincial Neurosciences, University of Cambridge, UK
  • Prof. John O’Brien, Dept. of Psychiatry, University of Cambridge, UK
  • Prof. Trevor W. Robbins, Dep. Of Experimental Psychology, University of Cambridge, UK
  • Prof. Pietro Lió, Computer Lab, University of Cambridge, UK
  • Prof. Antonio Terracciano, Department of Geriatrics, Florida State University College of Medicine, Tallahassee, USA
  • Prof. Jeffrey Staab, Departments of Psychiatry and Psychology and Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, United States

Selected recent publications

Toschi, N. & Passamonti, L. “Intra-cortical myelin mediates personality differences”. J Pers 87, 889-902, doi:10.1111/jopy.12442 (2019)

Spasov, S., Passamonti, L., Duggento, A., Lio, P., Toschi, N. & Alzheimer’s Disease Neuroimaging, I. “A parameter-efficient deep learning approach to predict conversion from mild cognitive impairment to Alzheimer’s disease”. Neuroimage 189, 276-287, doi:10.1016/j.neuroimage.2019.01.031 (2019).

Passamonti, L., Tsvetanov, K. A., Jones, P. S., Bevan-Jones, W. R., Arnold, R., Borchert, R. J., Mak, E., Su, L., O’Brien, J. T. & Rowe, J. B. “Neuroinflammation and Functional Connectivity in Alzheimer’s Disease: Interactive Influences on Cognitive Performance”. J Neurosci 39, 7218-7226, doi:10.1523/JNEUROSCI.2574-18.2019 (2019).

Passamonti, L., Riccelli, R., Indovina, I., Duggento, A., Terracciano, A. & Toschi, N. “Time-resolved connectome of the five-factor model of personality”. Sci Rep 9, 15066, doi:10.1038/s41598-019-51469-2 (2019).

Nigro, S., Indovina, I., Riccelli, R., Chiarella, G., Petrolo, C., Lacquaniti, F., Staab, J. P. & Passamonti, L. “Reduced cortical folding in multi-modal vestibular regions in persistent postural perceptual dizziness”. Brain Imaging Behav 13, 798-809, doi:10.1007/s11682-018-9900-6 (2019).

Toschi, N., Riccelli, R., Indovina, I., Terracciano, A. & Passamonti, L. “Functional connectome of the five-factor model of personality”. Personal Neurosci 1, doi:10.1017/pen.2017.2 (2018). 

Passamonti, L., Rodriguez, P. V., Hong, Y. T., Allinson, K. S. J., Bevan-Jones, W. R., Williamson, D., Jones, P. S., Arnold, R., Borchert, R. J., Surendranathan, A., Mak, E., Su, L., Fryer, T. D., Aigbirhio, F. I., O’Brien, J. T. & Rowe, J. B. “[(11)C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy”. Neurology 90, e1989-e1996, doi:10.1212/WNL.0000000000005610 (2018).

Passamonti, L., Riccelli, R., Lacquaniti, F., Staab, J. P. & Indovina, I. “Brain responses to virtual reality visual motion stimulation are affected by neurotic personality traits in patients with persistent postural-perceptual dizziness”. J Vestib Res 28, 369-378, doi:10.3233/VES-190653 (2018).

Passamonti, L., Lansdall, C. J. & Rowe, J. B. “The neuroanatomical and neurochemical basis of apathy and impulsivity in frontotemporal lobar degeneration”. Curr Opin Behav Sci 22, 14-20, doi:10.1016/j.cobeha.2017.12.015 (2018).

Riccelli, R., Toschi, N., Nigro, S., Terracciano, A. & Passamonti, L. “Surface-based morphometry reveals the neuroanatomical basis of the five-factor model of personality”. Soc Cogn Affect Neurosci 12, 671-684, doi:10.1093/scan/nsw175 (2017).

Riccelli, R., Indovina, I., Staab, J. P., Nigro, S., Augimeri, A., Lacquaniti, F. & Passamonti, L. “Neuroticism modulates brain visuo-vestibular and anxiety systems during a virtual rollercoaster task”. Hum Brain Mapp 38, 715-726, doi:10.1002/hbm.23411 (2017).

Passamonti, L., Vazquez Rodriguez, P., Hong, Y. T., Allinson, K. S., Williamson, D., Borchert, R. J., Sami, S., Cope, T. E., Bevan-Jones, W. R., Jones, P. S., Arnold, R., Surendranathan, A., Mak, E., Su, L., Fryer, T. D., Aigbirhio, F. I., O’Brien, J. T. & Rowe, J. B. “18F-AV-1451 positron emission tomography in Alzheimer’s disease and progressive supranuclear palsy”. Brain 140, 781-791, doi:10.1093/brain/aww340 (2017).

Fairchild, G., Toschi, N., Sully, K., Sonuga-Barke, E. J., Hagan, C. C., Diciotti, S., Goodyer, I. M., Calder, A. J. & Passamonti, L. “Mapping the structural organization of the brain in conduct disorder: replication of findings in two independent samples”. J Child Psychol Psychiatry 57, 1018-1026, doi:10.1111/jcpp.12581 (2016).